GPS (Group-based Prediction System) can predict kinase-specific phosphorylation sites for 408 human PKs in hierarchy. A large-scale prediction of more than 13,000 mammalian phosphorylation sites is given. In addition, a proteome-wide prediction of Aurora-B specific substrates including protein-protein interaction information is also provided. GPS will be a useful tool for further experimental consideration and construction of phosphorylation networks.
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